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Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model

Epigenetic disruption has been implicated in many diseases of aging, and age-associated DNA methylation changes at specific genomic loci in humans are strongly correlated with chronological age. The aim of this study was to explore the specificity of selected age-associated differentially methylated...

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Detalles Bibliográficos
Autores principales: Spiers, Helen, Hannon, Eilis, Wells, Sara, Williams, Brenda, Fernandes, Cathy, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846/
https://www.ncbi.nlm.nih.gov/pubmed/26861500
http://dx.doi.org/10.1016/j.mad.2016.02.001