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Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model
Epigenetic disruption has been implicated in many diseases of aging, and age-associated DNA methylation changes at specific genomic loci in humans are strongly correlated with chronological age. The aim of this study was to explore the specificity of selected age-associated differentially methylated...
Autores principales: | Spiers, Helen, Hannon, Eilis, Wells, Sara, Williams, Brenda, Fernandes, Cathy, Mill, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ireland
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846/ https://www.ncbi.nlm.nih.gov/pubmed/26861500 http://dx.doi.org/10.1016/j.mad.2016.02.001 |
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