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Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation

Faithful chromosome segregation in mammalian cells requires the bi-orientation of sister chromatids which relies on sensing correct attachments between spindle microtubules and kinetochores. Although the mechanisms underlying cyclin-dependent kinase 1 (CDK1) activation that triggers mitotic entry is...

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Detalles Bibliográficos
Autores principales: Mo, Fei, Zhuang, Xiaoxuan, Liu, Xing, Yao, Phil Y., Qin, Bo, Su, Zeqi, Zang, Jianye, Wang, Zhiyong, Zhang, Jiancun, Dou, Zhen, Tian, Changlin, Teng, Maikun, Niu, Liwen, Hill, Donald L., Fang, Guowei, Ding, Xia, Fu, Chuanhai, Yao, Xuebiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798883/
https://www.ncbi.nlm.nih.gov/pubmed/26829474
http://dx.doi.org/10.1038/nchembio.2017