Autopalmitoylation of TEAD Proteins Regulates Transcriptional Output of Hippo Pathway

TEA domain (TEAD) transcription factors bind to the co-activator YAP/TAZ, and regulate the transcriptional output of Hippo pathway, playing critical roles in organ size control and tumorigenesis. Protein S-palmitoylation attaches fatty acid (palmitate) to cysteine residues, and regulates protein tra...

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Detalles Bibliográficos
Autores principales: Chan, PuiYee, Han, Xiao, Zheng, Baohui, DeRan, Michael, Yu, Jianzhong, Jarugumilli, Gopala K., Deng, Hua, Pan, Duojia, Luo, Xuelian, Wu, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798901/
https://www.ncbi.nlm.nih.gov/pubmed/26900866
http://dx.doi.org/10.1038/nchembio.2036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798901/
https://www.ncbi.nlm.nih.gov/pubmed/26900866
http://dx.doi.org/10.1038/nchembio.2036

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