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Autopalmitoylation of TEAD Proteins Regulates Transcriptional Output of Hippo Pathway
TEA domain (TEAD) transcription factors bind to the co-activator YAP/TAZ, and regulate the transcriptional output of Hippo pathway, playing critical roles in organ size control and tumorigenesis. Protein S-palmitoylation attaches fatty acid (palmitate) to cysteine residues, and regulates protein tra...
Autores principales: | Chan, PuiYee, Han, Xiao, Zheng, Baohui, DeRan, Michael, Yu, Jianzhong, Jarugumilli, Gopala K., Deng, Hua, Pan, Duojia, Luo, Xuelian, Wu, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798901/ https://www.ncbi.nlm.nih.gov/pubmed/26900866 http://dx.doi.org/10.1038/nchembio.2036 |
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