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Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein

Non-segmented, (-)RNA viruses cause serious human diseases. Human metapneumovirus (HMPV), an emerging pathogen of this order of viruses (Mononegavirales) is one of the main causes of respiratory tract illness in children. To help elucidate the assembly mechanism of the nucleocapsid (the viral RNA ge...

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Detalles Bibliográficos
Autores principales: Renner, Max, Bertinelli, Mattia, Leyrat, Cédric, Paesen, Guido C, Saraiva de Oliveira, Laura Freitas, Huiskonen, Juha T, Grimes, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798948/
https://www.ncbi.nlm.nih.gov/pubmed/26880565
http://dx.doi.org/10.7554/eLife.12627