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Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells
Pluripotency transcription programs by core transcription factors (CTFs) might be reset during M/G1 transition to maintain the pluripotency of embryonic stem cells (ESCs). However, little is known about how CTFs are governed during cell cycle progression. Here, we demonstrate that the regulation of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798952/ https://www.ncbi.nlm.nih.gov/pubmed/26880562 http://dx.doi.org/10.7554/eLife.10877 |