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No current evidence for widespread dosage compensation in S. cerevisiae

Previous studies of laboratory strains of budding yeast had shown that when gene copy number is altered experimentally, RNA levels generally scale accordingly. This is true when the copy number of individual genes or entire chromosomes is altered. In a recent study, Hose et al. (2015) reported that...

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Detalles Bibliográficos
Autores principales: Torres, Eduardo M, Springer, Michael, Amon, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798953/
https://www.ncbi.nlm.nih.gov/pubmed/26949255
http://dx.doi.org/10.7554/eLife.10996