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Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis

It is currently unknown whether the molecular steps of large dense-core vesicle (LDCV) docking and priming are identical to the corresponding reactions in synaptic vesicle (SV) exocytosis. Munc13s are essential for SV docking and priming, and we systematically analyzed their role in LDCV exocytosis...

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Detalles Bibliográficos
Autores principales: Man, Kwun Nok M, Imig, Cordelia, Walter, Alexander M, Pinheiro, Paulo S, Stevens, David R, Rettig, Jens, Sørensen, Jakob B, Cooper, Benjamin H, Brose, Nils, Wojcik, Sonja M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798968/
https://www.ncbi.nlm.nih.gov/pubmed/26575293
http://dx.doi.org/10.7554/eLife.10635