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Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker

Building a sophisticated protein nano-assembly requires a method for linking protein components in a predictable and stable structure. Most of the cross linkers available have flexible spacers. Because of this, the linked hybrids have significant structural flexibility and the relative structure bet...

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Detalles Bibliográficos
Autores principales: Jeong, Woo Hyeon, Lee, Haerim, Song, Dong Hyun, Eom, Jae-Hoon, Kim, Sun Chang, Lee, Hee-Seung, Lee, Hayyoung, Lee, Jie-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799363/
https://www.ncbi.nlm.nih.gov/pubmed/26980593
http://dx.doi.org/10.1038/ncomms11031