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Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker
Building a sophisticated protein nano-assembly requires a method for linking protein components in a predictable and stable structure. Most of the cross linkers available have flexible spacers. Because of this, the linked hybrids have significant structural flexibility and the relative structure bet...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799363/ https://www.ncbi.nlm.nih.gov/pubmed/26980593 http://dx.doi.org/10.1038/ncomms11031 |