Site-targeted mutagenesis for stabilization of recombinant monoclonal antibody expressed in tobacco (Nicotiana tabacum) plants

This study examined the degradation pattern of a murine IgG1κ monoclonal antibody expressed in and extracted from transformed Nicotiana tabacum. Gel electrophoresis of leaf extracts revealed a consistent pattern of recombinant immunoglobulin bands, including intact and full-length antibody, as well...

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Detalles Bibliográficos
Autores principales: Hehle, Verena K., Paul, Matthew J., Roberts, Victoria A., van Dolleweerd, Craig J., Ma, Julian K.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799508/
https://www.ncbi.nlm.nih.gov/pubmed/26712217
http://dx.doi.org/10.1096/fj.15-283226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799508/
https://www.ncbi.nlm.nih.gov/pubmed/26712217
http://dx.doi.org/10.1096/fj.15-283226

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