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Site-targeted mutagenesis for stabilization of recombinant monoclonal antibody expressed in tobacco (Nicotiana tabacum) plants
This study examined the degradation pattern of a murine IgG1κ monoclonal antibody expressed in and extracted from transformed Nicotiana tabacum. Gel electrophoresis of leaf extracts revealed a consistent pattern of recombinant immunoglobulin bands, including intact and full-length antibody, as well...
Autores principales: | Hehle, Verena K., Paul, Matthew J., Roberts, Victoria A., van Dolleweerd, Craig J., Ma, Julian K.-C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799508/ https://www.ncbi.nlm.nih.gov/pubmed/26712217 http://dx.doi.org/10.1096/fj.15-283226 |
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