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Characterization of multiple sequence alignment errors using complete-likelihood score and position-shift map

BACKGROUND: Reconstruction of multiple sequence alignments (MSAs) is a crucial step in most homology-based sequence analyses, which constitute an integral part of computational biology. To improve the accuracy of this crucial step, it is essential to better characterize errors that state-of-the-art...

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Detalles Bibliográficos
Autor principal: Ezawa, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799563/
https://www.ncbi.nlm.nih.gov/pubmed/26992851
http://dx.doi.org/10.1186/s12859-016-0945-5