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Understanding the obstacle of incompatibility at residue 156 within HLA-B*35 subtypes

Defining permissive and non-permissive mismatches for transplantation is a demanding challenge. Single mismatches at amino acid (AA) position 156 of human leucocyte antigen (HLA) class I have been described to alter the peptide motif, repertoire, or mode of peptide loading through differential inter...

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Detalles Bibliográficos
Autores principales: Manandhar, Trishna, Kunze-Schumacher, Heike, Huyton, Trevor, Celik, Alexander A., Blasczyk, Rainer, Bade-Doeding, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799800/
https://www.ncbi.nlm.nih.gov/pubmed/26758079
http://dx.doi.org/10.1007/s00251-015-0896-4