Droxinostat, a Histone Deacetylase Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cell Lines via Activation of the Mitochondrial Pathway and Downregulation of FLIP()

Background: The current chemotherapeutic outcomes for hepatocellular carcinoma (HCC) are not encouraging, and long-term survival of this patient group remains poor. Recent studies have demonstrated the utility of histone deacetylase inhibitors that can disrupt cell proliferation and survival in HCC...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Li, Guangming, Wang, Xiang, Wang, Liang, Zhao, Rui, Wang, Juanxia, Kong, Yin, Ding, Jie, Li, Juan, Zhang, Lingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800063/
https://www.ncbi.nlm.nih.gov/pubmed/26947884
http://dx.doi.org/10.1016/j.tranon.2016.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800063/
https://www.ncbi.nlm.nih.gov/pubmed/26947884
http://dx.doi.org/10.1016/j.tranon.2016.01.004

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