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NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats

PCBs, widespread endocrine disruptors, cause the disturbance of thyroid hormone (TH) homeostasis in humans and animals. However, the exact mechanism of thyroid dysfunction caused by PCBs is still unknown. In order to clarify the hypotheses that NADPH oxidase (NOX) and subsequent NF-κB pathway may pl...

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Detalles Bibliográficos
Autores principales: Abliz, Ablikim, Chen, Chen, Deng, Wenhong, Wang, Weixing, Sun, Rongze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800090/
https://www.ncbi.nlm.nih.gov/pubmed/27047545
http://dx.doi.org/10.1155/2016/8354745