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Effect of Novel Melanocortin Type 2 Receptor Antagonists on the Corticosterone Response to ACTH in the Neonatal Rat Adrenal Gland In Vivo and In Vitro

Stress-induced increases in neonatal corticosterone demonstrate a unique shift from ACTH independence to ACTH dependence between postnatal day 2 (PD2) and day 8 (PD8) in newborn rats. This shift could be due to the binding of a bioactive, non-­immunoreactive plasma ligand to the adrenocortical melan...

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Detalles Bibliográficos
Autores principales: Nensey, Nasha K., Bodager, Jonathan, Gehrand, Ashley L., Raff, Hershel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800183/
https://www.ncbi.nlm.nih.gov/pubmed/27047449
http://dx.doi.org/10.3389/fendo.2016.00023