Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism

Therapy resistance remains a major problem in estrogen receptor-α (ERα)-positive breast cancer. A subgroup of ERα-positive breast cancer is characterized by mosaic presence of a minor population of ERα-negative cancer cells expressing the basal cytokeratin-5 (CK5). These CK5-positive cells are thera...

Descripción completa

Detalles Bibliográficos
Autores principales: Goodman, C R, Sato, T, Peck, A R, Girondo, M A, Yang, N, Liu, C, Yanac, A F, Kovatich, A J, Hooke, J A, Shriver, C D, Mitchell, E P, Hyslop, T, Rui, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800289/
https://www.ncbi.nlm.nih.gov/pubmed/26096934
http://dx.doi.org/10.1038/onc.2015.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800289/
https://www.ncbi.nlm.nih.gov/pubmed/26096934
http://dx.doi.org/10.1038/onc.2015.193

Ejemplares similares