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Glioma invasion mediated by the p75 neurotrophin receptor (p75(NTR)/CD271) requires regulated interaction with PDLIM1

The invasive nature of glioblastoma renders them incurable by current therapeutic interventions. Using a novel invasive human glioma model, we previously identified the neurotrophin receptor p75(NTR) (aka CD271) as a mediator of glioma invasion. Herein, we provide evidence that preventing phosphoryl...

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Detalles Bibliográficos
Autores principales: Ahn, B Y, Saldanha-Gama, R F G, Rahn, J J, Hao, X, Zhang, J, Dang, N-H, Alshehri, M, Robbins, S M, Senger, D L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800290/
https://www.ncbi.nlm.nih.gov/pubmed/26119933
http://dx.doi.org/10.1038/onc.2015.199