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Androgen receptors are acquired by healthy postmenopausal endometrial epithelium and their subsequent loss in endometrial cancer is associated with poor survival

BACKGROUND: Endometrial cancer (EC) is a hormone-driven disease, and androgen receptor (AR) expression in high-grade EC (HGEC) and metastatic EC has not yet been described. METHODS: The expression pattern and prognostic value of AR in relation to oestrogen (ERα and ERβ) and progesterone (PR) recepto...

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Detalles Bibliográficos
Autores principales: Kamal, A M, Bulmer, J N, DeCruze, S B, Stringfellow, H F, Martin-Hirsch, P, Hapangama, D K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800292/
https://www.ncbi.nlm.nih.gov/pubmed/26930451
http://dx.doi.org/10.1038/bjc.2016.16