Cargando…

Androgen receptors are acquired by healthy postmenopausal endometrial epithelium and their subsequent loss in endometrial cancer is associated with poor survival

BACKGROUND: Endometrial cancer (EC) is a hormone-driven disease, and androgen receptor (AR) expression in high-grade EC (HGEC) and metastatic EC has not yet been described. METHODS: The expression pattern and prognostic value of AR in relation to oestrogen (ERα and ERβ) and progesterone (PR) recepto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kamal, A M, Bulmer, J N, DeCruze, S B, Stringfellow, H F, Martin-Hirsch, P, Hapangama, D K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800292/ https://www.ncbi.nlm.nih.gov/pubmed/26930451 http://dx.doi.org/10.1038/bjc.2016.16

Ejemplares similares

Aberrant Dyskerin Expression Is Related to Proliferation and Poor Survival in Endometrial Cancer
por: Alnafakh, Rafah, et al.
Publicado: (2021)

Infrared spectroscopy with multivariate analysis to interrogate endometrial tissue: a novel and objective diagnostic approach
por: Taylor, S E, et al.
Publicado: (2011)

Harmonisation of biobanking standards in endometrial cancer research
por: Adishesh, M, et al.
Publicado: (2017)

Expression of N-acetylglucosaminyltransferase V in endometrial cancer correlates with poor prognosis
por: Yamamoto, E, et al.
Publicado: (2007)

High AGR2 protein is a feature of low grade endometrial cancer cells
por: Kamal, Areege, et al.
Publicado: (2018)

Tetraspanin CD151 is a novel prognostic marker in poor outcome endometrial cancer
por: Voss, M A, et al.
Publicado: (2011)

Pair-Box (PAX8) protein-positive expression is associated with poor disease outcome in women with endometrial cancer
por: Mhawech-Fauceglia, P, et al.
Publicado: (2012)

Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome
por: Krakstad, C, et al.
Publicado: (2012)

Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer
por: Sugihara, Takeru, et al.
Publicado: (2016)

Impact of genomic stability on protein expression in endometrioid endometrial cancer
por: Lomnytska, M I, et al.
Publicado: (2012)

A clinically applicable molecular-based classification for endometrial cancers
por: Talhouk, A, et al.
Publicado: (2015)

The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas
por: Shoji, K, et al.
Publicado: (2009)

L1CAM expression in endometrial carcinomas: an ENITEC collaboration study
por: van der Putten, Louis JM, et al.
Publicado: (2016)

Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer
por: Ino, K, et al.
Publicado: (2006)

Diagnostic and prognostic impact of serum HE4 detection in endometrial carcinoma patients
por: Bignotti, E, et al.
Publicado: (2011)

Expression of HER-2 affects patient survival and paclitaxel sensitivity in endometrial cancer
por: Mori, N, et al.
Publicado: (2010)

Preoperative neutrophil:lymphocyte and platelet:lymphocyte ratios predict endometrial cancer survival
por: Cummings, M, et al.
Publicado: (2015)

Similar protein expression profiles of ovarian and endometrial high-grade serous carcinomas
por: Hiramatsu, Kosuke, et al.
Publicado: (2016)

Human Endometrial Carcinogenesis Is Associated with Significant Reduction in Long Non-Coding RNA, TERRA
por: Adishesh, Meera, et al.
Publicado: (2020)

Prognostic significance of gamma-glutamyltransferase in patients with endometrial cancer: a multi-centre trial
por: Seebacher, V, et al.
Publicado: (2012)

Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers
por: Attarha, S, et al.
Publicado: (2013)

Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients
por: Tangen, Ingvild L, et al.
Publicado: (2017)

pHH3 and survivin are co-expressed in high-risk endometrial cancer and are prognostic relevant
por: Brunner, A, et al.
Publicado: (2012)

Prediction model for regional or distant recurrence in endometrial cancer based on classical pathological and immunological parameters
por: Versluis, M A, et al.
Publicado: (2015)

Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas
por: Haldorsen, I S, et al.
Publicado: (2014)

Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas
por: Bignotti, E, et al.
Publicado: (2008)

Associations between hepatocyte growth factor, c-Met, and basic fibroblast growth factor and survival in endometrial cancer patients
por: Felix, A S, et al.
Publicado: (2012)

HE4 is a novel tissue marker for therapy response and progestin resistance in medium- and low-risk endometrial hyperplasia
por: Ørbo, Anne, et al.
Publicado: (2016)

Prostate cancer bone metastases acquire resistance to androgen deprivation via WNT5A-mediated BMP-6 induction
por: Lee, G T, et al.
Publicado: (2014)

Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma
por: Engelsen, I B, et al.
Publicado: (2008)

Prognostic importance of CDK4/6-specific activity as a predictive marker for recurrence in patients with endometrial cancer, with or without adjuvant chemotherapy
por: Ikeda, Yuji, et al.
Publicado: (2015)

Intracrine androgen biosynthesis in renal cell carcinoma
por: Lee, Geun Taek, et al.
Publicado: (2017)

Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cells
por: Terakawa, T, et al.
Publicado: (2009)

Androgen-related expression of G-proteins in ovarian cancer
por: Sheach, L A, et al.
Publicado: (2009)

Implications of telomeres and telomerase in endometrial pathology
por: Hapangama, D.K., et al.
Publicado: (2017)

Apical MUC1 expression revealed on the foveolar epithelium in H. pylori gastritis
por: Rashid, M, et al.
Publicado: (2013)

Endometrial Intracrinology: Oestrogens, Androgens and Endometrial Disorders
por: Gibson, Douglas A., et al.
Publicado: (2018)

Phosphorylation of the androgen receptor is associated with reduced survival in hormone-refractory prostate cancer patients
por: McCall, P, et al.
Publicado: (2008)

Effects of platelet-activating factor and its differential regulation by androgens and steroid hormones in prostate cancers
por: Xu, B, et al.
Publicado: (2013)

Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
por: Kawano, Y, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_8u772mq9qaeje4lfqqf3cqe47u