Androgen deprivation in LNCaP prostate tumour xenografts induces vascular changes and hypoxic stress, resulting in promotion of epithelial-to-mesenchymal transition

BACKGROUND: When single-agent androgen deprivation therapy (ADT) is administered for locally advanced prostate cancer, men usually relapse within 1–2 years with more malignant castrate-resistant disease. The reason for this is currently unknown. We now hypothesise that an initial treatment response...

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Detalles Bibliográficos
Autores principales: Byrne, N M, Nesbitt, H, Ming, L, McKeown, S R, Worthington, J, McKenna, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800298/
https://www.ncbi.nlm.nih.gov/pubmed/26954717
http://dx.doi.org/10.1038/bjc.2016.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800298/
https://www.ncbi.nlm.nih.gov/pubmed/26954717
http://dx.doi.org/10.1038/bjc.2016.29

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