Quantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment

Breast cancer is a heterogeneous disease, at both an inter- and intra-tumoural level. Appreciating heterogeneity through the application of biomarkers and molecular signatures adds complexity to tumour taxonomy but is key to personalising diagnosis, treatment and prognosis. The extent to which heter...

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Detalles Bibliográficos
Autores principales: Buckley, Niamh E., Forde, Claire, McArt, Darragh G., Boyle, David P., Mullan, Paul B., James, Jacqueline A., Maxwell, Perry, McQuaid, Stephen, Salto-Tellez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800308/
https://www.ncbi.nlm.nih.gov/pubmed/26996207
http://dx.doi.org/10.1038/srep23383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800308/
https://www.ncbi.nlm.nih.gov/pubmed/26996207
http://dx.doi.org/10.1038/srep23383

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