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Quantification of HER2 heterogeneity in breast cancer–implications for identification of sub-dominant clones for personalised treatment
Breast cancer is a heterogeneous disease, at both an inter- and intra-tumoural level. Appreciating heterogeneity through the application of biomarkers and molecular signatures adds complexity to tumour taxonomy but is key to personalising diagnosis, treatment and prognosis. The extent to which heter...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800308/ https://www.ncbi.nlm.nih.gov/pubmed/26996207 http://dx.doi.org/10.1038/srep23383 |