Deletion of Galectin-3 Enhances Xenobiotic Induced Murine Primary Biliary Cholangitis by Facilitating Apoptosis of BECs and Release of Autoantigens

Galectin-3 (Gal-3) is a carbohydrate binding lectin, with multiple roles in inflammatory diseases and autoimmunity including its antiapoptotic effect on epithelial cells. In particular, increased expression of Gal-3 in epithelial cells is protective from apoptosis. Based on the thesis that apoptosis...

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Detalles Bibliográficos
Autores principales: Arsenijevic, Aleksandar, Milovanovic, Marija, Milovanovic, Jelena, Stojanovic, Bojana, Zdravkovic, Natasa, Leung, Patrick S.C., Liu, Fu-Tong, Gershwin, M. Eric, Lukic, Miodrag L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800400/
https://www.ncbi.nlm.nih.gov/pubmed/26996208
http://dx.doi.org/10.1038/srep23348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800400/
https://www.ncbi.nlm.nih.gov/pubmed/26996208
http://dx.doi.org/10.1038/srep23348

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