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Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms

The exact roles of acid-sensing ion channels (ASICs) in synaptic plasticity remain elusive. Here, we address the contribution of ASIC1a to five forms of synaptic plasticity in the mouse hippocampus using an in vitro multi-electrode array recording system. We found that genetic deletion or pharmacolo...

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Detalles Bibliográficos
Autores principales: Liu, Ming-Gang, Li, Hu-Song, Li, Wei-Guang, Wu, Yan-Jiao, Deng, Shi-Ning, Huang, Chen, Maximyuk, Oleksandr, Sukach, Volodymyr, Krishtal, Oleg, Zhu, Michael X., Xu, Tian-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800407/
https://www.ncbi.nlm.nih.gov/pubmed/26996240
http://dx.doi.org/10.1038/srep23350