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In vivo imaging of prostate cancer using an anti-PSMA scFv fragment as a probe

We aimed to evaluate a fluorescent-labeled single chain variable fragment (scFv) of the anti-PSMA antibody as a specific probe for the detection of prostate cancer by in vivo fluorescence imaging. An orthotopic model of prostate cancer was generated by injecting LNCaP cells into the prostate lobe. S...

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Detalles Bibliográficos
Autores principales: Mazzocco, Claire, Fracasso, Giulio, Germain-Genevois, Coralie, Dugot-Senant, Nathalie, Figini, Mariangela, Colombatti, Marco, Grenier, Nicolas, Couillaud, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800420/
https://www.ncbi.nlm.nih.gov/pubmed/26996325
http://dx.doi.org/10.1038/srep23314