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Multiplexed single-molecule force spectroscopy using a centrifuge

We present a miniature centrifuge force microscope (CFM) that repurposes a benchtop centrifuge for high-throughput single-molecule experiments with high-resolution particle tracking, a large force range, temperature control and simple push-button operation. Incorporating DNA nanoswitches to enable r...

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Detalles Bibliográficos
Autores principales: Yang, Darren, Ward, Andrew, Halvorsen, Ken, Wong, Wesley P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800429/
https://www.ncbi.nlm.nih.gov/pubmed/26984516
http://dx.doi.org/10.1038/ncomms11026