Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

Cell replacement therapy with human pluripotent stem cell-derived neurons has the potential to ameliorate neurodegenerative dysfunction and central nervous system injuries, but reprogrammed neurons are dissociated and spatially disorganized during transplantation, rendering poor cell survival, funct...

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Detalles Bibliográficos
Autores principales: Carlson, Aaron L., Bennett, Neal K., Francis, Nicola L., Halikere, Apoorva, Clarke, Stephen, Moore, Jennifer C., Hart, Ronald P., Paradiso, Kenneth, Wernig, Marius, Kohn, Joachim, Pang, Zhiping P., Moghe, Prabhas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800432/
https://www.ncbi.nlm.nih.gov/pubmed/26983594
http://dx.doi.org/10.1038/ncomms10862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800432/
https://www.ncbi.nlm.nih.gov/pubmed/26983594
http://dx.doi.org/10.1038/ncomms10862

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