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Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia

Therapeutic hypothermia (HT) is standard care for moderate and severe neonatal hypoxic-ischaemic encephalopathy (HIE), the leading cause of permanent brain injury in term newborns. However, the optimal temperature for HT is still unknown, and few preclinical studies have compared multiple HT treatme...

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Detalles Bibliográficos
Autores principales: Wood, Thomas, Osredkar, Damjan, Puchades, Maja, Maes, Elke, Falck, Mari, Flatebø, Torun, Walløe, Lars, Sabir, Hemmen, Thoresen, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800445/
https://www.ncbi.nlm.nih.gov/pubmed/26997257
http://dx.doi.org/10.1038/srep23430