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Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus

This study is designed to examine the cellular functions of human Fas-associated factor 1 (FAF1) containing multiple ubiquitin-related domains. Microarray analyses revealed that interferon-stimulated genes related to the antiviral response are significantly increased in FAF1-knockdown HeLa cells. Si...

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Detalles Bibliográficos
Autores principales: Song, Soonhwa, Lee, Jae-Jin, Kim, Hee-Jung, Lee, Jeong Yoon, Chang, Jun, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800795/
https://www.ncbi.nlm.nih.gov/pubmed/26811330
http://dx.doi.org/10.1128/MCB.00744-15