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Tongxinluo Reverses the Hypoxia-suppressed Claudin-9 in Cardiac Microvascular Endothelial Cells

BACKGROUND: Claudin-5, claudin-9, and claudin-11 are expressed in endothelial cells to constitute tight junctions, and their deficiency may lead to hyperpermeability, which is the initiating process and pathological basis of cardiovascular disease. Although tongxinluo (TXL) has satisfactory antiangi...

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Detalles Bibliográficos
Autores principales: Liu, Kun, Wang, Xiu-Juan, Li, Yan-Ning, Li, Bin, Qi, Jin-Sheng, Zhang, Jing, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800845/
https://www.ncbi.nlm.nih.gov/pubmed/26879018
http://dx.doi.org/10.4103/0366-6999.176076