Cargando…

Tongxinluo Reverses the Hypoxia-suppressed Claudin-9 in Cardiac Microvascular Endothelial Cells

BACKGROUND: Claudin-5, claudin-9, and claudin-11 are expressed in endothelial cells to constitute tight junctions, and their deficiency may lead to hyperpermeability, which is the initiating process and pathological basis of cardiovascular disease. Although tongxinluo (TXL) has satisfactory antiangi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Kun, Wang, Xiu-Juan, Li, Yan-Ning, Li, Bin, Qi, Jin-Sheng, Zhang, Jing, Wang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800845/ https://www.ncbi.nlm.nih.gov/pubmed/26879018 http://dx.doi.org/10.4103/0366-6999.176076

Ejemplares similares

Tongxinluo Inhibits Cyclooxygenase-2, Inducible Nitric Oxide Synthase, Hypoxia-inducible Factor-2α/Vascular Endothelial Growth Factor to Antagonize Injury in Hypoxia-stimulated Cardiac Microvascular Endothelial Cells
por: Li, Yan-Ning, et al.
Publicado: (2015)

Cardiac Microvascular Barrier Function Mediates the Protection of Tongxinluo against Myocardial Ischemia/Reperfusion Injury
por: Qi, Kang, et al.
Publicado: (2015)

Tongxinluo (TXL), a Traditional Chinese Medicinal Compound, Improves Endothelial Function After Chronic Hypoxia Both In Vivo and In Vitro
por: Zheng, Cui-Ying, et al.
Publicado: (2015)

Sequential transplantation of exosomes and mesenchymal stem cells pretreated with a combination of hypoxia and Tongxinluo efficiently facilitates cardiac repair
por: Xiong, Yuyan, et al.
Publicado: (2022)

Tongxinluo Prevents Endothelial Dysfunction Induced by Homocysteine Thiolactone In Vivo via Suppression of Oxidative Stress
por: Zhang, Yi, et al.
Publicado: (2015)

Tongxinluo enhances the effect of atorvastatin on the treatment of atherosclerosis with chronic obstructive pulmonary disease by maintaining the pulmonary microvascular barrier
por: Kuang, Xiangnan, et al.
Publicado: (2022)

Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia
por: Yu, Ping, et al.
Publicado: (2021)

RUNX3 modulates hypoxia-induced endothelial-to-mesenchymal transition of human cardiac microvascular endothelial cells
por: Liu, Yanhua, et al.
Publicado: (2017)

The Effect of Velvet Antler Proteins on Cardiac Microvascular Endothelial Cells Challenged with Ischemia-Hypoxia
por: Xiao, Xiang, et al.
Publicado: (2017)

Tongxinluo attenuates oxygen-glucose-serum deprivation/restoration-induced endothelial barrier breakdown via peroxisome proliferator activated receptor-α/angiopoietin-like 4 pathway in high glucose-incubated human cardiac microvascular endothelial cells
por: Qi, Kang, et al.
Publicado: (2020)

Traditional Chinese Medicine Tongxinluo Improves Cardiac Function of Rats with Dilated Cardiomyopathy
por: Shen, Fang-Fang, et al.
Publicado: (2014)

Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease
por: Gu, Jiao-Jiao, et al.
Publicado: (2023)

Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition
por: Yin, Yujie, et al.
Publicado: (2019)

Tongxinluo promotes axonal plasticity and functional recovery after stroke
por: Wang, Xiaoting, et al.
Publicado: (2020)

Tongxinluo Improves Cardiac Function and Ameliorates Ventricular Remodeling in Mice Model of Myocardial Infarction through Enhancing Angiogenesis
por: Bai, Wen-Wu, et al.
Publicado: (2013)

Endothelial Claudin: Claudin-5/Tmvcf Constitutes Tight Junction Strands in Endothelial Cells
por: Morita, Kazumasa, et al.
Publicado: (1999)

Influenza Infects Lung Microvascular Endothelium Leading to Microvascular Leak: Role of Apoptosis and Claudin-5
por: Armstrong, Susan M., et al.
Publicado: (2012)

Tongxinluo attenuates reperfusion injury in diabetic hearts by angiopoietin-like 4-mediated protection of endothelial barrier integrity via PPAR-α pathway
por: Qi, Kang, et al.
Publicado: (2018)

Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of P18 through claudin7
por: Liu, Hong, et al.
Publicado: (2016)

Tongxinluo Improves Apolipoprotein E-Deficient Mouse Heart Function
por: Yuan, Guo-Qiang, et al.
Publicado: (2018)

Correction: Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of p18 through claudin7
por: Liu, Hong, et al.
Publicado: (2021)

Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia
por: Cohen, Emily B., et al.
Publicado: (2020)

Effects of tongxinluo on the neointima formation and expression of inflammatory cytokines in rats after carotid artery balloon injury
por: Yao, En-Hui, et al.
Publicado: (2014)

Scutellarin-treated exosomes increase claudin 5, occludin and ZO1 expression in rat brain microvascular endothelial cells
por: Zhong, Xiaoqin, et al.
Publicado: (2019)

FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells
por: Zhang, Shenwei, et al.
Publicado: (2013)

Effect of Tongxinluo on Nephrin Expression via Inhibition of Notch1/Snail Pathway in Diabetic Rats
por: Cui, Fangqiang, et al.
Publicado: (2015)

Inhibiting leukocyte‐endothelial cell interactions by Chinese medicine Tongxinluo capsule alleviates no‐reflow after arterial recanalization in ischemic stroke
por: Liu, Shen, et al.
Publicado: (2023)

Correction: FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells
por: Zhang, Shenwei, et al.
Publicado: (2013)

ITGA9 Inhibits Proliferation and Migration of Dermal Microvascular Endothelial Cells in Psoriasis
por: Hou, Hui, et al.
Publicado: (2022)

Tongxinluo Exerts Inhibitory Effects on Pyroptosis and Amyloid-β Peptide Accumulation after Cerebral Ischemia/Reperfusion in Rats
por: Wang, Bing, et al.
Publicado: (2021)

Chinese Patent Medicine Tongxinluo Capsule for Hypertension: A Systematic Review of Randomised Controlled Trials
por: Wang, Jie, et al.
Publicado: (2014)

Tongxinluo Capsule Combined with Atorvastatin for Coronary Heart Disease: A Systematic Review and Meta-Analysis
por: Liu, Qiao, et al.
Publicado: (2021)

Tongxinluo capsule in combination with conventional therapies for stable angina pectoris: A meta-analysis and systematic review
por: Feng, Ruli, et al.
Publicado: (2023)

PGC-1α Mediated Peripheral Nerve Protection of Tongxinluo in STZ-Induced Diabetic Rats
por: Cui, Xiaopei, et al.
Publicado: (2016)

N-n-butyl haloperidol iodide ameliorates hypoxia/reoxygenation injury through modulating the LKB1/AMPK/ROS pathway in cardiac microvascular endothelial cells
por: Lu, Binger, et al.
Publicado: (2016)

Curcumin suppresses intestinal microvascular endothelial cells invasion and angiogenesis induced by activated platelets
por: Xu, Su, et al.
Publicado: (2019)

Exosomal Signaling during Hypoxia Mediates Microvascular Endothelial Cell Migration and Vasculogenesis
por: Salomon, Carlos, et al.
Publicado: (2013)

Hyperoxia Reprogrammes Microvascular Endothelial Cell Response to Hypoxia in an Organ-Specific Manner
por: Reiterer, Moritz, et al.
Publicado: (2022)

FGF21 Protects Against Hypoxia Injury Through Inducing HSP72 in Cerebral Microvascular Endothelial Cells
por: Wang, Hao-Wei, et al.
Publicado: (2019)

Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related Proteins
por: Shi, Meina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2b0ocp3306u420c01mfqaekiv0