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Computational and nonglycosylated systems: a simpler approach for development of nanosized PEGylated proteins
Cysteine PEGylation includes several steps, and is difficult to manage in practice. In the current investigation, the cysteine PEGylation of erythropoietin analogs was examined using computational and nonglycosylated systems to define a simpler approach for specific PEGylation. Two model analogs (E3...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801162/ https://www.ncbi.nlm.nih.gov/pubmed/27042012 http://dx.doi.org/10.2147/DDDT.S98323 |