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Computational and nonglycosylated systems: a simpler approach for development of nanosized PEGylated proteins

Cysteine PEGylation includes several steps, and is difficult to manage in practice. In the current investigation, the cysteine PEGylation of erythropoietin analogs was examined using computational and nonglycosylated systems to define a simpler approach for specific PEGylation. Two model analogs (E3...

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Detalles Bibliográficos
Autores principales:	Mirzaei, Hadi, Kazemi, Bahram, Bandehpour, Mojgan, Shoari, Alireza, Asgary, Vahid, Ardestani, Mehdi Shafiee, Madadkar-Sobhani, Armin, Cohan, Reza Ahangari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801162/ https://www.ncbi.nlm.nih.gov/pubmed/27042012 http://dx.doi.org/10.2147/DDDT.S98323

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