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Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5’-Flanking Region

Oestrogens influence the pathology and development of hormone-sensitive breast cancers. Tissue factor pathway inhibitor (TFPI) has been shown to be associated with breast cancer pathogenesis. Recently, we found TFPI mRNA levels to be significantly reduced by oestrogens in a breast cancer cell line (...

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Detalles Bibliográficos
Autores principales: Ali, Huda Omar, Stavik, Benedicte, Myklebust, Christiane Filion, Andersen, Elisabeth, Dahm, Anders E. A., Iversen, Nina, Sandset, Per Morten, Skretting, Grethe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801176/
https://www.ncbi.nlm.nih.gov/pubmed/26999742
http://dx.doi.org/10.1371/journal.pone.0152114