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IL-6 Signaling in Myelomonocytic Cells Is Not Crucial for the Development of IMQ-Induced Psoriasis

Psoriasis is an autoimmune skin disease that is associated with aberrant activity of immune cells and keratinocytes. In mice, topical application of TLR7/8 agonist IMQ leads to a skin disorder resembling human psoriasis. Recently, it was shown that the IL-23/ IL-17 axis plays a deciding role in the...

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Detalles Bibliográficos
Autores principales: Klebow, Sabrina, Hahn, Matthias, Nikoalev, Alexei, Wunderlich, F. Thomas, Hövelmeyer, Nadine, Karbach, Susanne H., Waisman, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801375/
https://www.ncbi.nlm.nih.gov/pubmed/26999594
http://dx.doi.org/10.1371/journal.pone.0151913