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The colorectal cancer immune paradox revisited

Tumor infiltrating lymphocytes (TILs) represent a strong independent predictor of relapse and overall survival in colorectal cancer (CRC). However, it appears that a majority of CRCs, i.e., microsatellite stable (MSS) tumors, are refractory to immune checkpoint blockers. The results of recent compre...

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Detalles Bibliográficos
Autores principales: Angelova, Mihaela, Charoentong, Pornpimol, Hackl, Hubert, Trajanoski, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801462/
https://www.ncbi.nlm.nih.gov/pubmed/27057454
http://dx.doi.org/10.1080/2162402X.2015.1078058