Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment

Oncolytic virotherapy is an emergent promising therapeutic approach for the treatment of cancer. We have constructed a vaccinia virus (WR strain) deleted for thymidine kinase (TK) and ribonucleotide reductase (RR) genes that expressed the fusion suicide gene FCU1 derived from the yeast cytosine deam...

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Detalles Bibliográficos
Autores principales: Fend, Laetitia, Remy-Ziller, Christelle, Foloppe, Johann, Kempf, Juliette, Cochin, Sandrine, Barraud, Luc, Accart, Nathalie, Erbs, Philippe, Fournel, Sylvie, Préville, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801465/
https://www.ncbi.nlm.nih.gov/pubmed/27057460
http://dx.doi.org/10.1080/2162402X.2015.1080414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801465/
https://www.ncbi.nlm.nih.gov/pubmed/27057460
http://dx.doi.org/10.1080/2162402X.2015.1080414

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