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High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies

Stem cell therapies can promote neural repair and regeneration, yet controversy regarding optimal cell source and mechanism of action has slowed clinical translation, potentially due to undefined cellular heterogeneity. Single-cell resolution is needed to identify clinically relevant subpopulations...

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Detalles Bibliográficos
Autores principales: Rennert, Robert C., Schäfer, Richard, Bliss, Tonya, Januszyk, Michael, Sorkin, Michael, Achrol, Achal S., Rodrigues, Melanie, Maan, Zeshaan N., Kluba, Torsten, Steinberg, Gary K., Gurtner, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801858/
https://www.ncbi.nlm.nih.gov/pubmed/27047447
http://dx.doi.org/10.3389/fneur.2016.00041