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Synergy between Common γ Chain Family Cytokines and IL-18 Potentiates Innate and Adaptive Pathways of NK Cell Activation

Studies to develop cell-based therapies for cancer and other diseases have consistently shown that purified human natural killer (NK) cells secrete cytokines and kill target cells after in vitro culture with high concentrations of cytokines. However, these assays poorly reflect the conditions that a...

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Detalles Bibliográficos
Autores principales: Nielsen, Carolyn M., Wolf, Asia-Sophia, Goodier, Martin R., Riley, Eleanor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801862/
https://www.ncbi.nlm.nih.gov/pubmed/27047490
http://dx.doi.org/10.3389/fimmu.2016.00101