Role of Anticonvulsants in the Management of Posttraumatic Epilepsy

Posttraumatic seizures (PTS) have been recognized as a major complication of traumatic brain injury (TBI). The annual incidence of TBI in the United States is 1.7 million. The role of anticonvulsants in the treatment of posttraumatic epilepsy (PTE) remains uncertain. Based on current studies, howeve...

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Autores principales: Kirmani, Batool F., Robinson, Diana Mungall, Fonkem, Ekokobe, Graf, Kevin, Huang, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801868/
https://www.ncbi.nlm.nih.gov/pubmed/27047441
http://dx.doi.org/10.3389/fneur.2016.00032
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author Kirmani, Batool F.
Robinson, Diana Mungall
Fonkem, Ekokobe
Graf, Kevin
Huang, Jason H.
author_facet Kirmani, Batool F.
Robinson, Diana Mungall
Fonkem, Ekokobe
Graf, Kevin
Huang, Jason H.
author_sort Kirmani, Batool F.
collection PubMed
description Posttraumatic seizures (PTS) have been recognized as a major complication of traumatic brain injury (TBI). The annual incidence of TBI in the United States is 1.7 million. The role of anticonvulsants in the treatment of posttraumatic epilepsy (PTE) remains uncertain. Based on current studies, however, anticonvulsants have been shown to reduce early PTS occurring within the first 7 days, but little to no benefits have been shown in late PTS occurring after 7 days. In this paper, we provide a mini review of the role of anticonvulsants and current advances in the management of PTE.
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spelling pubmed-48018682016-04-04 Role of Anticonvulsants in the Management of Posttraumatic Epilepsy Kirmani, Batool F. Robinson, Diana Mungall Fonkem, Ekokobe Graf, Kevin Huang, Jason H. Front Neurol Neuroscience Posttraumatic seizures (PTS) have been recognized as a major complication of traumatic brain injury (TBI). The annual incidence of TBI in the United States is 1.7 million. The role of anticonvulsants in the treatment of posttraumatic epilepsy (PTE) remains uncertain. Based on current studies, however, anticonvulsants have been shown to reduce early PTS occurring within the first 7 days, but little to no benefits have been shown in late PTS occurring after 7 days. In this paper, we provide a mini review of the role of anticonvulsants and current advances in the management of PTE. Frontiers Media S.A. 2016-03-22 /pmc/articles/PMC4801868/ /pubmed/27047441 http://dx.doi.org/10.3389/fneur.2016.00032 Text en Copyright © 2016 Kirmani, Robinson, Fonkem, Graf and Huang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kirmani, Batool F.
Robinson, Diana Mungall
Fonkem, Ekokobe
Graf, Kevin
Huang, Jason H.
Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
title Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
title_full Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
title_fullStr Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
title_full_unstemmed Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
title_short Role of Anticonvulsants in the Management of Posttraumatic Epilepsy
title_sort role of anticonvulsants in the management of posttraumatic epilepsy
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801868/
https://www.ncbi.nlm.nih.gov/pubmed/27047441
http://dx.doi.org/10.3389/fneur.2016.00032
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