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β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon

Leukocyte recruitment is pivotal for the initiation and perpetuation of inflammatory bowel disease (IBD) and controlled by the specificity and interactions of chemokines and adhesion molecules. Interactions of the adhesion molecules α4β7-integrin and mucosal addressin cell-adhesion molecule-1 (MAdCA...

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Detalles Bibliográficos
Autores principales: Schippers, A, Muschaweck, M, Clahsen, T, Tautorat, S, Grieb, L, Tenbrock, K, Gaßler, N, Wagner, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801899/
https://www.ncbi.nlm.nih.gov/pubmed/26349655
http://dx.doi.org/10.1038/mi.2015.82