Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency

Transcription factor Stat3 directs self‐renewal of pluripotent mouse embryonic stem (ES) cells downstream of the cytokine leukemia inhibitory factor (LIF). Stat3 upregulates pivotal transcription factors in the ES cell gene regulatory network to sustain naïve identity. Stat3 also contributes to the...

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Detalles Bibliográficos
Autores principales: Carbognin, Elena, Betto, Riccardo M, Soriano, Maria E, Smith, Austin G, Martello, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801951/
https://www.ncbi.nlm.nih.gov/pubmed/26903601
http://dx.doi.org/10.15252/embj.201592629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801951/
https://www.ncbi.nlm.nih.gov/pubmed/26903601
http://dx.doi.org/10.15252/embj.201592629

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