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A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer
Numerical centrosome aberrations underlie certain developmental abnormalities and may promote cancer. A cell maintains normal centrosome numbers by coupling centrosome duplication with segregation, which is achieved through sustained association of each centrosome with a mitotic spindle pole. Althou...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802056/ https://www.ncbi.nlm.nih.gov/pubmed/26987684 http://dx.doi.org/10.1038/ncomms11005 |