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Improved dialytic removal of protein-bound uraemic toxins with use of albumin binding competitors: an in vitro human whole blood study

Protein-bound uraemic toxins (PBUTs) cause various deleterious effects in end-stage kidney disease patients, because their removal by conventional haemodialysis (HD) is severely limited by their low free fraction in plasma. Here we provide an experimental validation of the concept that the HD dialyt...

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Detalles Bibliográficos
Autores principales: Tao, Xia, Thijssen, Stephan, Kotanko, Peter, Ho, Chih-Hu, Henrie, Michael, Stroup, Eric, Handelman, Garry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802219/
https://www.ncbi.nlm.nih.gov/pubmed/27001248
http://dx.doi.org/10.1038/srep23389