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Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

Forced overexpression and/or downregulation of proteins regulating epithelial-to-mesenchymal transition (EMT) has been reported to alter metastasis by changing migration and stem cell capacity of tumor cells. However, these manipulations artificially keep cells in fixed states, while in vivo cells m...

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Detalles Bibliográficos
Autores principales: Beerling, Evelyne, Seinstra, Daniëlle, de Wit, Elzo, Kester, Lennart, van der Velden, Daphne, Maynard, Carrie, Schäfer, Ronny, van Diest, Paul, Voest, Emile, van Oudenaarden, Alexander, Vrisekoop, Nienke, van Rheenen, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802222/
https://www.ncbi.nlm.nih.gov/pubmed/26947068
http://dx.doi.org/10.1016/j.celrep.2016.02.034