Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

One approach to identifying cancer-specific vulnerabilities and therapeutic targets is to profile genetic dependencies in cancer cell lines. Here, we describe data from a series of siRNA screens that identify the kinase genetic dependencies in 117 cancer cell lines from ten cancer types. By integrat...

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Detalles Bibliográficos
Autores principales: Campbell, James, Ryan, Colm J., Brough, Rachel, Bajrami, Ilirjana, Pemberton, Helen N., Chong, Irene Y., Costa-Cabral, Sara, Frankum, Jessica, Gulati, Aditi, Holme, Harriet, Miller, Rowan, Postel-Vinay, Sophie, Rafiq, Rumana, Wei, Wenbin, Williamson, Chris T., Quigley, David A., Tym, Joe, Al-Lazikani, Bissan, Fenton, Timothy, Natrajan, Rachael, Strauss, Sandra J., Ashworth, Alan, Lord, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802229/
https://www.ncbi.nlm.nih.gov/pubmed/26947069
http://dx.doi.org/10.1016/j.celrep.2016.02.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802229/
https://www.ncbi.nlm.nih.gov/pubmed/26947069
http://dx.doi.org/10.1016/j.celrep.2016.02.023

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