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Single-cell lineage tracking analysis reveals that an established cell line comprises putative cancer stem cells and their heterogeneous progeny

Mammalian cell culture has been used in many biological studies on the assumption that a cell line comprises putatively homogeneous clonal cells, thereby sharing similar phenotypic features. This fundamental assumption has not yet been fully tested; therefore, we developed a method for the chronolog...

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Detalles Bibliográficos
Autores principales: Sato, Sachiko, Rancourt, Ann, Sato, Yukiko, Satoh, Masahiko S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802345/
https://www.ncbi.nlm.nih.gov/pubmed/27003384
http://dx.doi.org/10.1038/srep23328