Cargando…

Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility

Protein degradation mediated by the proteasome is important for the protein homeostasis. Various proteasome activators, such as PA28 and PA200, regulate the proteasome function. Here we show double knockout (dKO) mice of Psme3 and Psme4 (genes for PA28γ and PA200), but not each single knockout mice,...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Lin, Haratake, Kousuke, Miyahara, Hatsumi, Chiba, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802386/
https://www.ncbi.nlm.nih.gov/pubmed/27003159
http://dx.doi.org/10.1038/srep23171